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Gain of function. Unfortunately, by now everyone should know what it means. It’s the deliberate amplification of aspects of a pathogen that sensible (albeit nonexpert) people might consider undesirable. In particular, it includes efforts directed at making an infectious agent more communicable, more resistant to countermeasures, and/or more lethal to its victims.
As I type this, gain of function experimentation is going on in thousands of laboratories across the United States under the misguided supervision of people who often fancy themselves knowledgeable experts qualified to engage in such a dangerous project. The pathogen in question is racism, something to which humans are by nature susceptible but for which we have developed, over hundreds of years, fairly simple and effective preventative treatments.