Contributor Post Created with Sketch. Saturday Night Science: A Troublesome Inheritance

 

A Troublesome Inheritance by Nicholas WadeGeographically isolated populations of a species (unable to interbreed with others of their kind) will be subject to natural selection based upon their environment. If that environment differs from that of other members of the species, the isolated population will begin to diverge genetically, as genetic endowments which favour survival and more offspring are selected for. If the isolated population is sufficiently small, the mechanism of genetic drift may cause a specific genetic variant to become almost universal or absent in that population. If this process is repeated for a sufficiently long time, isolated populations may diverge to such a degree they can no longer interbreed, and therefore become distinct species.

None of this is controversial when discussing other species, but in some circles to suggest that these mechanisms apply to humans is the deepest heresy. This well-researched book examines the evidence, much from molecular biology which has become available only in recent years, for the diversification of the human species into distinct populations, or “races” if you like, after its emergence from its birthplace in Africa. In this book the author argues that human evolution has been “recent, copious, and regional” and presents the genetic evidence to support this view.

A few basic facts should be noted at the outset. All humans are members of a single species, and all can interbreed. Humans, as a species, have an extremely low genetic diversity compared to most other animal species: this suggests that our ancestors went through a genetic “bottleneck” where the population was reduced to a very small number, causing the variation observed in other species to be lost through genetic drift. You might expect different human populations to carry different genes, but this is not the case—all humans have essentially the same set of genes. Variation among humans is mostly a result of individuals carrying different alleles (variants) of a gene. For example, eye colour in humans is entirely inherited: a baby’s eye colour is determined completely by the alleles of various genes inherited from the mother and father. You might think that variation among human populations is then a question of their carrying different alleles of genes, but that too is an oversimplification. Human genetic variation is, in most cases, a matter of the frequency of alleles among the population.

This means that almost any generalisation about the characteristics of individual members of human populations with different evolutionary histories is ungrounded in fact. The variation among individuals within populations is generally much greater than that of populations as a whole. Discrimination based upon an individual’s genetic heritage is not just abhorrent morally but scientifically unjustified.

Based upon these now well-established facts, some have argued that “race does not exist” or is a “social construct”. While this view may be motivated by a well-intentioned desire to eliminate discrimination, it is increasingly at variance with genetic evidence documenting the history of human populations.

Around 200,000 years ago, modern humans emerged in Africa. They spent more than three quarters of their history in that continent, spreading to different niches within it and developing a genetic diversity which today is greater than that of all humans in the rest of the world. Around 50,000 years before the present, by the genetic evidence, a small band of hunter-gatherers left Africa for the lands to the north. Then, some 30,000 years ago the descendants of these bands who migrated to the east and west largely ceased to interbreed and separated into what we now call the Caucasian and East Asian populations. These have remained the main three groups within the human species. Subsequent migrations and isolations have created other populations such as Australian and American aborigines, but their differentiation from the three main races is less distinct. Subsequent migrations, conquest, and intermarriage have blurred the distinctions between these groups, but the fact is that almost any child, shown a picture of a person of European, African, or East Asian ancestry can almost always effortlessly and correctly identify their area of origin. University professors, not so much: it takes an intellectual to deny the evidence of one’s own eyes.

As these largely separated populations adapted to their new homes, selection operated upon their genomes. In the ancestral human population children lost the ability to digest lactose, the sugar in milk, after being weaned from their mothers’ milk. But in populations which domesticated cattle and developed dairy farming, parents who passed on an allele which would allow their children to drink cow’s milk their entire life would have more surviving offspring and, in a remarkably short time on the evolutionary scale, lifetime lactose tolerance became the norm in these areas. Among populations which never raised cattle or used them only for meat, lifetime lactose tolerance remains rare today.

Humans in Africa originally lived close to the equator and had dark skin to protect them from the ultraviolet radiation of the Sun. As human bands occupied northern latitudes in Europe and Asia, dark skin would prevent them from being able to synthesise sufficient Vitamin D from the wan, oblique sunlight of northern winters. These populations were under selection pressure for alleles of genes which gave them lighter skin, but interestingly Europeans and East Asians developed completely different genetic means to lighten their skin. The selection pressure was the same, but evolution blundered into two distinct pathways to meet the need.

Can genetic heritage affect behaviour? There’s evidence it can. Humans carry a gene called MAO-A, which breaks down neurotransmitters that affect the transmission of signals within the brain. Experiments in animals have provided evidence that under-production of MAO-A increases aggression and humans with lower levels of MAO-A are found to be more likely to commit violent crime. MAO-A production is regulated by a short sequence of DNA adjacent to the gene: humans may have anywhere from two to five copies of the promoter; the more you have, the more the MAO-A, and hence the mellower you’re likely to be. Well, actually, people with three to five copies are indistinguishable, but those with only two (2R) show higher rates of delinquency. Among men of African ancestry, 5.5% carry the 2R variant, while 0.1% of Caucasian males and 0.00067% of East Asian men do. Make of this what you will.

The author argues that just as the introduction of dairy farming tilted the evolutionary landscape in favour of those bearing the allele which allowed them to digest milk into adulthood, the transition of tribal societies to cities, states, and empires in Asia and Europe exerted a selection pressure upon the population which favoured behavioural traits suited to living in such societies. While a tribal society might benefit from producing a substantial population of aggressive warriors, an empire has little need of them: its armies are composed of soldiers, courageous to be sure, who follow orders rather than charging independently into battle. In such a society, the genetic traits which are advantageous in a hunter-gatherer or tribal society will be selected out, as those carrying them will, if not expelled or put to death for misbehaviour, be unable to raise as large a family in these settled societies.

Perhaps, what has been happening over the last five millennia or so is a domestication of the human species. Precisely as humans have bred animals to live with them in close proximity, human societies have selected for humans who are adapted to prosper within them. Those who conform to the social hierarchy, work hard, come up with new ideas but don’t disrupt the social structure will have more children and, over time, whatever genetic predispositions there may be for these characteristics (which we don’t know today) will become increasingly common in the population. It is intriguing that as humans settled into fixed communities, their skeletons became less robust. This same process of gracilisation is seen in domesticated animals compared to their wild congeners. Certainly there have been as many human generations since the emergence of these complex societies as have sufficed to produce major adaptation in animal species under selective breeding.

Far more speculative and controversial is whether this selection process has been influenced by the nature of the cultures and societies which create the selection pressure. East Asian societies tend to be hierarchical, obedient to authority, and organised on a large scale. European societies, by contrast, are fractious, fissiparous, and prone to bottom-up insurgencies. Is this in part the result of genetic predispositions which have been selected for over millennnia in societies which work that way?

It is assumed by many right-thinking people that all that is needed to bring liberty and prosperity to those regions of the world which haven’t yet benefited from them is to create the proper institutions, educate the people, and bootstrap the infrastructure, then stand back and watch them take off. Well, maybe—but the history of colonialism, the mission civilisatrice, and various democracy projects and attempts at nation building over the last two centuries may suggest it isn’t that simple. The population of the colonial, conquering, or development-aid-giving power has the benefit of millennia of domestication and adaptation to living in a settled society with division of labour. Its adaptations for tribalism have been largely bred out. Not so in many cases for the people they’re there to “help”. Withdraw the colonial administration or occupation troops and before long tribalism will re-assert itself because that’s the society for which the people are adapted.

Suggesting things like this is anathema in academia or political discourse. But look at the plain evidence of post-colonial Africa and more recent attempts of nation-building, and couple that with the emerging genetic evidence of variation in human populations and connections to behaviour and you may find yourself thinking forbidden thoughts. This book is an excellent starting point to explore these difficult issues, with numerous citations of recent scientific publications.

Wade, Nicholas. A Troublesome Inheritance. New York: Penguin Press, 2014. ISBN 978-1-59420-446-3.

Here is a painful-to-watch discussion with the author produced by the American Anthropological Association. The audio quality is mediocre, and Mr Wade’s connection is intermittent (and hence he only gets to speak after the designated “attack anthropologist” has his say).

 

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  1. The Question Inactive

    Man With the Axe: This is true and important when making certain (but not all) decisions about individuals. However, when making public policy decisions about groups it makes sense to take group characteristics into account. This is why the concept of disparate impact is so pernicious. It leads to perverse outcomes such as race-norming the results of perfectly fair tests when those results don’t reflect a false group equality.

    Yes. It is completely erroneous to assume group difference amount to racism.

    • #91
    • December 8, 2014, at 8:03 AM PST
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  2. The Question Inactive

    (quoted wrong part, starting over)

    • #92
    • December 8, 2014, at 8:05 AM PST
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  3. James Gawron Thatcher
    James GawronJoined in the first year of Ricochet Ricochet Charter Member

    Tuck:

    John Walker: But in populations which domesticated cattle and developed dairy farming, parents who passed on an allele which would allow their children to drink cow’s milk their entire life would have more surviving offspring and, in a remarkably short time on the evolutionary scale, lifetime lactose tolerance became the norm in these areas. Among populations which never raised cattle or used them only for meat, lifetime lactose tolerance remains rare today.

    This is a great story, but in fact “lactose tolerance” appears to have little to do with lifetime consumption of dairy. Populations that are most reknowned for their dairy consumption may have low incidence of this gene, and some populations with the highest incidence do not consume dairy.

    I don’t know why this gene has spread so quickly, but it’s not required for healthy consumption of dairy—that much is perfectly clear.

    Tuck & John,

    This is what has been called since Steven J. Gould an evolutionary ‘just so’ story. Dr. Berlinski, Claire’s father, is most expert at revealing the absurdities of too easily assuming shallow evolutionary analysis to be scientifically binding.

    Now let me add to this the possibility of a Marxist racial social construct ‘just so’ story. The standard treatment, recently increased in sophistication by Edward Said, is that slavery is the result of the inherent racism in White Capitalist European Colonialist Society. What this fails to notice is the fact that slavery had been practiced as far back as recorded History can document. In Said’s case he failed to notice that in the 9th century Islam sailed down the east coast of Africa (Kenya included) conquering the ports and setting up the most sophisticated slave trade in human history. Islam has always practiced slavery and still does to this day. Said fails to notice that England voted an end to slavery and America fought a civil war at the expense of many citizens to end slavery, all long before the Bolshevik Revolution in 1917.

    The facts don’t fit the Marxist meta-narrative. We could call the Marxist meta-narrative an historical ‘just so’ story.

    Regards,

    Jim

    • #93
    • December 8, 2014, at 8:16 AM PST
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  4. The Question Inactive

    MJBubba: Here is the bottleneck. 1 Peter 3:20: …when God’s patience waited in the days of Noah, while the ark was being prepared, in which a few, that is, eight persons, were brought safely through water.

    That thought had occurred to me. All of the information I’ve heard on this has indicated the bottleneck was around 10,000 people. I don’t know enough about genetics to know if it could have been a lot less. I do think it is extremely difficult to accept the story of Noah’s Ark literally without resorting to supernatural explanations (which science can’t disprove). Stories of an ancient flood are very common in different cultures, so I imagine that they refer to something real, although I doubt it was a literal worldwide flood. A flood that was so large that for the people experiencing it thought the whole world was flooding seems completely plausible.

    • #94
    • December 8, 2014, at 8:17 AM PST
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  5. The Question Inactive

    Tuck: Populations that are most reknowned for their dairy consumption may have low incidence of this gene, and some populations with the highest incidence do not consume dairy.

    Which populations consume dairy but are lactose intolerant? Do they drink the milk fresh and full of lactose, or do they ferment the milk into yogurt etc. to digest the lactose?

    • #95
    • December 8, 2014, at 8:35 AM PST
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  6. Tuck Inactive

    Michael Sanregret: Which populations consume dairy but are lactose intolerant? Do they drink the milk fresh and full of lactose, or do they ferment the milk into yogurt etc. to digest the lactose?

    The Maasai, for starters. They drink it both raw and fermented.

    “Our findings, however, are quite different. The Masai, also a traditional pastoral cattle raising nomadic people, are now classed as Nilotic (formerly Nilo-Hamitic). They have a prevalence of lactose malabsorption of 62% in our sample. Despite this, the Masai drink large quantities of milk each day without symptoms.”

    Lactose malabsorption among Masai children of East Africa.”

    • #96
    • December 8, 2014, at 9:13 AM PST
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  7. Fred Cole Member

    Son of Spengler: The more relevant question is whether history itself may be shaped by genetics. If different local geographic conditions led to evolution of subtlely different forms of social organization, we should not ignore the implications of genetics on, e.g., the emergence of different forms of government.

    That’s all based on the idea that social forms are based on genetics. They’re far more easily explained by history.

    • #97
    • December 8, 2014, at 9:59 AM PST
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  8. Son of Spengler Contributor

    Fred Cole:

    Son of Spengler: The more relevant question is whether history itself may be shaped by genetics. If different local geographic conditions led to evolution of subtlely different forms of social organization, we should not ignore the implications of genetics on, e.g., the emergence of different forms of government.

    That’s all based on the idea that social forms are based on genetics. They’re far more easily explained by history.

    No, it’s a question, based on the understanding that humans are mammals and that animal social behavior is influenced by genetics. Your rejection of the line of questioning — insisting that history is simply “history” — is the more dogmatic approach.

    For example: Many colonial regimes had similar histories, yet different post-colonial outcomes. Conversely, many colonial regimes had different histories but similar post-colonial outcomes. Could something more fundamental than history explain this?

    • #98
    • December 8, 2014, at 10:18 AM PST
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  9. AIG Inactive

    Fred Cole: That’s all based on the idea that social forms are based on genetics. They’re far more easily explained by history.

    Far more easily explained, no. Genetics of course doesn’t “easily” explain much either.

    What genetics might explain is the development of “primitive” baseline institutions in ancient history, these being explained “more easily” by the natural endowments of the environment these people lived in. This acted as a form of natural selection of particular desirable traits.

    More complex social organizations that evolved in antiquity, probably not so much to do with genetics, because now we get human-induced natural selection, that is, the natural environment and endowment wasn’t as strong in selecting behavior as were the complex inter-society relationships: trade, exchange of ideas, invasions etc.

    But “history” is not an easy tool to be used to explain. There are so many possible historical variables, which are additive, that eventually you can’t simply come up with “easy” and “simple” explanations like…Karl Marx tried to do.

    But the real question here is what happens when relatively insulated populations where the natural environmental endowment continued to play a defining role in shaping behavior, such as in Africa or in Australia or Native Americans…meet the modern world.

    Adaptation does seem to be more problematic there, although some have obviously done it better than others.

    • #99
    • December 8, 2014, at 10:38 AM PST
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  10. AIG Inactive

    Son of Spengler: For example: Many colonial regimes had similar histories, yet different post-colonial outcomes. Conversely, many colonial regimes had different histories but similar post-colonial outcomes. Could something more fundamental than history explain this?

    http://economics.mit.edu/files/4123

    ;)

    • #100
    • December 8, 2014, at 10:40 AM PST
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  11. Mendel Member
    MendelJoined in the first year of Ricochet Ricochet Charter Member

    Tuck:

    John Walker:

    Populations that are most reknowned for their dairy consumption may have low incidence of this gene, and some populations with the highest incidence do not consume dairy.

    I don’t know why this gene has spread so quickly, but it’s not required for healthy consumption of dairy—that much is perfectly clear.

    Sorry to always be pestering you in these science threads, but I’m afraid I must again disagree quite strongly.

    There is an incredibly good correlation between societies which have domesticated cattle, lactose tolerance, and the genetic changes which allow for lifetime expression of the lactase enzyme. And contrary to your other comment, the Massai tribe does indeed appear to possess “the gene” (which is something of a misnomer) for lactose tolerance:

    Genetic Origins of Lactase Persistence and the Spread of Pastoralism in Africa

    (My guess is that the original paper you cited from 1979 misjudged the genetic basis of lactose (in)tolerance in Massai due to the somewhat crude test they used and the small sample size (21 people).)

    • #101
    • December 8, 2014, at 10:46 AM PST
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  12. Tuck Inactive

    Mendel: Sorry to always be pestering you in these science threads, but I’m afraid I must again disagree quite strongly.

    No problem. You ask good question and make good points.

    From your study: “We measured levels of lactose tolerance in 322 individuals… A 50 g lactose powder solution…”

    The study I quoted observed: “Leichter (12) has concluded that on the average, the intensity of symptoms in lactose intolerant individuals was highest with an aqueous lactose solution, lower with skim milk, and lowest with whole milk.”

    “…Garza and Scrimshaw (4) studied the relationship of milk intolerance to lactose intolerance in 99 children (69 black and 30 white) using graded quantities of milk. “Of the black children studied, 11% of those 4 to 5 years old, 50% of those 6 to 7 years old, and 72% of those 8 to 9 years old were found to be lactose-intolerant, yet no child was intolerant to 240 ml (8 oz) of milk.” Stephenson and Latham (6) also reported that lactose intolerant adults in their study could drink normal quantities of milk with no, or very mild symptoms ensuing.”

    So simply using a lactose tolerance test does not appear to be a good guide for the ability to digest milk. Which is the whole point of that paper: can milk be provided as a relief food to purportedly lactose-intolerant people? Answer: Yes.

    Part of the reason, of course, is that raw milk, of the sort the Maasai drink, comes with a load of lactobacilli which take up residence and aid in digestion of lactose, as would the lactobacilli consumed via fermented milk, which they also consume.

    Probiotics—compensation for lactase insufficiency

    So the lactase-persistence/dairy consumption nexis appears to proceed from a bunch of reasonable assumptions which do not survive verification.

    I’ll observe that there are several studies that found the same thing as with the Maasai in other milk-consuming populations.

    “The results of the LTT showed that 13 (62%) of the Masai are lactose malabsorbers, while 8 (38%) are lactose absorbers (Table 1).”

    “…somewhat crude test they used…”

    They fed them lactose and checked their blood glucose. How else would you measure lactase action in vivo? I’ll note this is the same test that is used everyday to measure glucose intolerance in diabetics… It’s also the same test that was used in the study you provided.

    Unlike the study you provided, however, they also looked for symptoms of lactose malabsorbtion, which is the important element in the ability to digest milk on a regular basis.

    • #102
    • December 8, 2014, at 11:59 AM PST
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  13. Profile Photo Member

    AIG:

    Son of Spengler: For example: Many colonial regimes had similar histories, yet different post-colonial outcomes. Conversely, many colonial regimes had different histories but similar post-colonial outcomes. Could something more fundamental than history explain this?

    http://economics.mit.edu/files/4123

    ;)

    An alternate view with which Nicholas Wade would probably be more likely to agree:

    http://www2.ku.edu/~kuwpaper/2010Papers/201206.pdf

    • #103
    • December 8, 2014, at 1:41 PM PST
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  14. Tom Meyer, Common Citizen Contributor

    BTW, Wade’s earlier book on human pre-history is also excellent. It and A Troubled Inheritance seem to cover some of the same ground, but have a lot of difference as well.

    • #104
    • December 8, 2014, at 2:00 PM PST
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  15. John Walker Contributor
    John Walker

    Tom Meyer, Ed.: BTW, Wade’s earlier book on human pre-history is also excellent.

    Before the Dawn was the topic of Saturday Night Science on 2014-01-11. (The date in the post was mangled when it was imported into Ricochet 2.0.) It’s a great book: highly recommended.

    • #105
    • December 8, 2014, at 2:19 PM PST
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  16. AIG Inactive

    wmartin: An alternate view with which Nicholas Wade would probably be more likely to agree: http://www2.ku.edu/~kuwpaper/2010Papers/201206.pdf

    Ehh…it’s ok. It’s an interesting study but a few things stand out:

    1) It’s not really showing “causation”…i.e they frame their arguments that IQ effects institutions. But their data can’t really show that, since its for 1 year and it’s just shows association.

    2) The “effect” of IQ is tiny, compared to all the other variables. So does it matter? Yes. Does it matter a lot…no.

    • #106
    • December 8, 2014, at 4:09 PM PST
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  17. AIG Inactive

    PS: What is more likely happening is the reverse of what they claim: i.e. institutional quality affects economic output, which affects IQ

    • #107
    • December 8, 2014, at 8:15 PM PST
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  18. Valiuth Member
    ValiuthJoined in the first year of Ricochet Ricochet Charter Member

    I think one thing to keep in mind when looking at the possible effects of genetics on social development is to keep in mind that the traits described, ie. intelligence, aggression, cooperativity are all very broad descriptions. Their actual detailed expression can vary drastically based on circumstance even while underlying genetics remains the same.

    For example a propensity for aggression driven by alterations in the genes regulating testosterone could be equally responsible for being expressed in committing a double homicide, being a great linebacker, or a very successful day trader. Traits are the confluence of our genes and the environment. As environment changes so do our prototypes even while our genes can remain intact.

    Considering that humans actively work to reshape our environment we must wonder what is really driving us. Frankly I lean more towards nurture when looking at the disparate state of world populations today. Our rate of cultural change and technological change has far out stripped our reproductive rate. Thus the environment in which humans live has been changing much faster than we have. In fact in many ways I might argue we are ill adapted to our modern world genetically, as some doctors/scientists have pointed out.

    • #108
    • December 8, 2014, at 9:00 PM PST
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  19. AIG Inactive

    Valiuth: Considering that humans actively work to reshape our environment we must wonder what is really driving us. Frankly I lean more towards nurture when looking at the disparate state of world populations today.

    Me too. We see this in IQ, for example. IQ can increase dramatically in a population, even if the genetic makeup doesn’t. I.e., it can increase much faster than genetic effects would imply.

    It’s also very sensitive to level of education, economic conditions etc. Does it have a genetic component? Of course it does. But that effect seems to be swamped by environmental conditions which are within our ability to change.

    • #109
    • December 8, 2014, at 10:31 PM PST
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  20. Profile Photo Member

    I am baffled by the Flynn Effect regardless, but there is a lot of doubt as to whether the Flynn Effect is a true increase in g.

    • #110
    • December 9, 2014, at 8:46 AM PST
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  21. The Question Inactive

    AIG:

    It’s also very sensitive to level of education, economic conditions etc. Does it have a genetic component? Of course it does. But that effect seems to be swamped by environmental conditions which are within our ability to change.

    Gene pools change too, in the long run. To the degree that intelligence differs in a racial, heritible way, it merely means that there is a higher concentration of “smart genes” in one population as opposed to another. The gene pool gets reshuffled each generation. I expect that in a culture where the same rules are applied to all races, genetic racial differences in intelligence would tend to diminish over generations.

    • #111
    • December 9, 2014, at 2:20 PM PST
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  22. AIG Inactive

    Michael Sanregret: The gene pool gets reshuffled each generation.

    Each generation? I doubt it. These things take a long time.

    • #112
    • December 9, 2014, at 5:43 PM PST
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  23. Jack Sarfatti Inactive

    https://www.youtube.com/watch?v=iOBHLlvrUe4

    Michael Savage interviews Nicholas Wade in his December 11, 2014 show here. It’s in the second hour of the show. However, the first hour is also of interest. Listen to Sidney Germansky’s story, for example. Start at about 50 minutes in for Wade prelude.

    • #113
    • December 11, 2014, at 6:25 PM PST
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